(PR122) Investigations of Novel Endodontic Sealers and Modifications of Existing Bioceramic Sealers

The first aim of this study was to determine if commercially available pulpal liners and crown and bridge cements could be used to seal endodontically treated canals. The second objective was to determine if reduction in particle size could improve the properties of an existing sealer. Materials and

Methods: One pulpal liner, Activa (Pulpadent), one crown and bridge cement Ceramir (Doxa), and EndoSequence BC sealer (Brasseler) were evaluated to determine if the repurposed materials could seal an endodontically treated canal with Endosequence as the control. The second part of this study modified a commercially available powder and liquid sealer, BioRoot (Septodont) BC sealer, to decrease its particle size and evaluated if this modification had any effect on its physical properties. 45 single-rooted teeth were decoronated, endodontically treated, and obturated using one of the commercially available products (n=3) Activa, Ceramir, Endosequence. The modified sealers were separated into groups by the time the powdered sealer was milled using a Speedmixer: 0 (control), 40, 60, 120 and 240 seconds. Data was analyzed using a one-way ANOVA and all pairs comparison using a post-hoc Tukey Kramer HSD test with an alpha >0.05.

Results: Of the repurposed materials, Activa showed the most promising results with a setting time of 2.5 +/- 0.9 hours as well as the best performance in terms of flow, film thickness, bond strength and leakage resistance. For the modified sealers, the mechanical properties increased as the milling times were increased for all except shear bond, where bond strength peaked at 7.9 +/- 6.9 MPa for 120 seconds of milling time.