(TC74) Clinical Application of Regenerative Endodontics: A Promising Treatment Alternative.

Regenerative endodontic procedures (REPs) provide a promising alternative to traditional apexification for managing immature permanent teeth with pulp necrosis. Compared to apexification, REPs promote continued root development, resulting in superior outcomes such as enhanced root length, wall thickness, and apical closure. Success in REPs is measured through three primary goals: elimination of symptoms and evidence of bony healing (primary), increased root wall thickness and/or root length (secondary), and positive responses to vitality testing (tertiary).

This case series highlights clinical outcomes from three REP cases, with treatments involving initial irrigation with 1.5% NaOCl and 17% EDTA, followed by the placement of calcium hydroxide for two weeks. At the second visit, anesthesia with 3% mepivacaine (without epinephrine) was administered, and further irrigation was performed using 17% EDTA. A Xshaper file at 1200RPM was extended beyond the apex to induce bleeding, providing a scaffold with a collaplug base, over which a 3 mm BC putty barrier was placed and then restored with resin.

This clinic table presents the outcomes and follow-ups of three clinical cases alongside the clinical and patient-related factors that may influence the success of REPs. This study underscores the potential of REPs to achieve favorable clinical outcomes and contribute to more biologically oriented endodontic care.