(PR037) Effectiveness of Pulpotomy Using Biodentine in Adults: A Systematic Review

Objective: This systematic review aimed to assess the clinical effectiveness of Biodentine as a pulpotomy material in adult patients, with a focus on post-operative pain and radiographic outcomes. Materials and

Methods: A comprehensive search of Scopus, Embase, Medline, and Web of Science databases was conducted in March 2024. Only randomized clinical trials (RCTs) published in English that evaluated pulpotomy outcomes using Biodentine in adults were included. The quality of studies was appraised using the revised Cochrane Risk of Bias tool (ROB-2) and GRADE criteria.

Results: Five RCTs involving 390 teeth met the inclusion criteria. Two studies were classified as high risk of bias, one as low risk, and two with some concerns. Despite these limitations, most studies found that Biodentine was comparable to other materials, such as Mineral Trioxide Aggregate (MTA), Total Fill, and TheraCal, in terms of pain reduction and radiographic healing. The overall quality of evidence was rated low, primarily due to the small number of trials and methodological concerns.

Conclusions: Current evidence suggests that Biodentine demonstrates effectiveness similar to traditional pulpotomy agents, but the quality of available evidence remains low. Larger, long-term studies are necessary to further validate these findings.