OR14 - Root Canal Treatment Outcomes in MIH-Affected Teeth: A Retrospective Study

Introduction: Treating Molar Incisor Hypomineralization (MIH) -affected teeth poses a significant challenge for endodontists due to their unique morphology, altered microbiome, and difficulties in achieving effective anesthesia. The long-term prognosis of these teeth remains uncertain. This study aimed to assess the outcomes of primary Root Canal Treatment (RCT) in teeth with and without MIH to determine if MIH affects the outcome of RCT. Materials and

Methods: This retrospective cohort study enrolled 418 patients ages 5-18 years who underwent routine endodontic therapy by a single provider. Participants were separated into MIH-affected (n=217) and non-MIH-affected (n=201). All cases had a 24–36-month follow-up. The primary outcome was categorized as “healed” for cases with no radiographic indications of apical periodontitis (PAI score of 1 or 2) and no clinical symptoms and “diseased” for cases with radiographic evidence of apical periodontitis (PAI score of 3 to 5) and clinical symptoms.

Results: Severe MIH-affected teeth had 83.3% favorable outcomes, significantly decreased compared to teeth not affected by MIH (97.5%). Logistic regression revealed that severe MIH significantly affected the outcome and reduced healing (OR=0.231, P=.013). Adequate coronal restorations significantly improved healing outcomes, especially in non-MIH teeth (OR=86.351, P=.002).

Conclusion: Teeth affected by MIH may yield less favorable outcomes following root canal treatment, necessitating careful consideration of treatment options for these cases and reinforcing the requirement of sealed restorations after endodontic therapy.