(PR029) Outcome of Using a Premixed Injectable Calcium Silicate Cement for Root-End Fillings in Endodontic Microsurgery: A Randomized Controlled Trial

Objective: The purpose of this randomized clinical trial was to evaluate the outcomes of endodontic microsurgery using a newly developed, premixed injectable calcium silicate cement, Endocem MTA Premixed (EMP), in comparison to ProRoot MTA (PMTA) as a retrograde filling material. Materials and methods: A total of 140 teeth meeting the inclusion criteria were randomly allocated to either the PMTA or EMP group. Endodontic microsurgery was performed by nine operators. Clinical and radiographic follow-ups were scheduled at 6 and 12 months, with cone-beam computed tomographic (CBCT) imaging after 12 months. Cases were considered successful if no clinical signs or symptoms were present and radiographs demonstrated complete or incomplete healing. Success rates were compared using Fisher’s exact test. Statistical analysis was conducted using IBM SPSS 27 (IBM Corp., Armonk, NY, USA), with significance set at P<0.05.

Results: Nine patients were excluded due to refusal, resulting in analysis of 131 teeth. Four patients reported pain or a chronic periapical abscess within 12 months post-surgery. Two underwent reoperation, and two required extraction. The overall success rates were 95.5% (63/66 teeth) for PMTA and 93.4% (57/61 teeth) for EMP. No significant association was found between the outcome and variables such as gender, tooth location, tooth type, or retrograde filling material (p>0.05).

Conclusion: These results suggest that EMP could be used as an alternative to PMTA as a root-end filling material in endodontic microsurgery.